科室及职务
诊疗专长
| 姓名 | 沈磊 |
| 出生年月 | 1972年8月 |
| 单位 | 武汉大学人民医院消化内科 |
| 所属学科 | 临床医学-内科学 |
| 职务、职称及头衔 | 科主任，教授，三级主任医师，博士生导师 |
| leishenwuhan@126.com | |
| 联系方式 | 027-88041911转82135 |
| 研究方向 |
1.消化内镜下胃肠疾病、消化道肿瘤的诊断，尤其擅长消化道早癌内镜下诊断； 2.消化道早癌内镜下治疗、功能性胃肠病的诊断与治疗； 3.炎症性肠病的诊断与治疗 |
| 个人简介 | |
| 主要擅长消化内镜下胃肠疾病的诊断和治疗、功能性胃肠病的诊断与治疗，尤其擅长早期食管、胃、肠癌的诊断和治疗，每年完成超过1000例消化内镜手术。以第一作者、通讯作者发表论文100余篇，其中SCI论文30余篇。主持国家级、省科技厅、省教委、省卫生厅项目7项，参与编写著作《消化道早癌蓝激光成像技术诊断图谱》、《实用消化病学》；已培养硕士研究生30余名，博士研究生4名。 | |
| 学术任职与荣誉 | |
| 湖北省微循环学会消化疾病微创诊疗学会主委、湖北省中西医结合学会消化内镜分会主委；湖北省医学会消化分会常委、湖北省医师协会消化分会常委兼秘书、武汉市消化病学会常委、幽门螺杆菌相关疾病专家委员会副主任委员、武汉医学会AI智能学组组长、武汉医学会第十九届消化病学分会常务委员、湖北省医学会消化病学分会第八届委员会常务委员、中华医学会消化病分会消化影像协作组委员、中华消化内镜学会隧道学组委员、中国医师协会内镜分会委员、中国医师协会消化医师分会结直肠学组委员、中华医学会消化内镜分会青年委员、早癌协作组委员湖北省中西医结合消化病专业委员、湖北省医学会胰腺病分会委员会委员、武汉市消化内镜学会委员。 | |
| 教育履历 | |
|
1987.09-1992.06湖北医学院临床医学专业获学士学位 1993.09-1996.06湖北医科大学（现武汉大学医学部）内科学获硕士学位 2000.09-2003.06武汉大学第一临床学院内科学获博士学位 |
|
| 工作履历 | |
|
1992.07-1996.12湖北医科大学附属第一医院住院医师 1999.08-2005.08武汉大学人民医院消化内科主治医师 2005.08-2011.08武汉大学人民医院消化内科副教授、副主任医师 2011.08-至今武汉大学人民医院消化内科教授主任医师 |
|
| 成果获奖 | |
|
1.《一种直肠内壁止血装置》2005年获湖北省科学技术进步三等奖； 2.《胃肠道肿瘤转移和化疗耐药的分子生物学特征及临床应用》2017年获湖北省科技进步二等奖；3.《消化道肿瘤人工智能内镜筛查诊断系统关键技术及应用》2021年获得湖北省技术发明一等奖。 |
|
| 代表性论著 | |
|
1．Double-nylon
purse-string suture in closing postoperative wounds following endoscopic
resection of large gastric submucosal
tumors.World Journal of Gastroenterology 2024. 2．A New Risk Score to Predict Intensive Care Unit Admission for Patients with Acute Pancreatitis 48 Hours After Admission: Multicenter Study.Digestive Diseases and Sciences 2023. 3．miR-200a attenuated oxidative stress, inflammation, and apoptosis in dextran sulfate sodium-induced colitis through activation of Nrf2.Frontiers in Immunology 2023. 4. Research hotspots and trend analysis of abdominal pain in inflammatory bowel disease: a bibliometric and visualized analysis.Frontiers in Pharmacology 2023. 5. A New Risk Score to Predict Intensive Care Unit Admission for Patients with Acute Pancreatitis 48 Hours After Admission: Multicenter Study.DIGESTIVE DISEASES AND SCIENCES 2022. 6. Machine learning model identifies aggressive acute pancreatitis within 48 h of admission: a large retrospective study.BMC MEDICAL INFORMATICS AND DECISION MAKING 2022. 7. CircRNA_0040705 promotes the progression of hepatocellular carcinoma. IUBMB LIFE 2022. 8. Inhibition of IRAK 1/4 alleviates colitis by inhibiting TLR4/ NF-κB pathway and protecting the intestinal barrier.Bosn J Basic Med Sci 2022.9. Clinical Efficacy of Endoscopic Submucosal Dissection for the Treatment of Duodenal Lesions in Terms of Operative Technique and Management of Complications.J Laparoendosc Adv Surg Tech A 2022. 10. Real-time artificial intelligence for detecting focal lesions and diagnosing neoplasms of the stomach by white-light endoscopy(with videos).2021 11.Pristimerin reduces dextran sulfate sodium-induced colitis in mice by inhibiting microRNA-155.Int Immunopharmacol.2021 12.Real-time artificial intelligence for detecting focal lesions and diagnosing neoplasms of the stomach by white-light endoscopy(with videos).Gastrointest Endosc.2021 13.Application of linked color imaging in the diagnosis of early gastrointestinal neoplasms and precancerous lesions: a review.Therap Adv Gastroenterol.2021 14. Eriodictyol attenuates dextran sodium sulphate-induced colitis in mice by regulating the sonic hedgehog signalling pathway.Pharm Biol.2021 15. Reciprocal induction of hepatitis C virus replication and stimulation of hepatic profibrogenic cytokine release and cellular viability by YKL-40.Ann Transl Med.2021 16.Poly(ADP ribose) polymerase 1 inhibitor ameliorates dextran sulfate sodium induced.Exp Ther Med.2021 17.Clinical Efficacy of Single-Channel Gastroscopy, Double-Channel Gastroscopy, and Double Gastroscopy for Submucosal Tumors in the Cardia and Gastric Fundus.2020 18.Salidroside attenuates dextran sulfate sodium-induced colitis in mice via SIRT1/FoxOs signaling pathway.2019 19.Diagnostic value of blue laser imaging combined with magnifying endoscopy for precancerous and early gastric cancer lesions.2019 20.Diagnostic ability of blue laser imaging combined with magnifying endoscopy for early esophageal cancer.2019 |
| Name | LEI SHEN |
| Date of birth | August，1972 |
| Department | Gatroenterology Department，Renmin Hospital,Wuhan University. |
| Title | Director of Gastroenterology I, Professor, Doctoral Supervisor |
| leishenwuhan@126.com | |
| TEL | 027-88041911-82135 |
| Research Direction | |
|
1. Diagnosis of gastrointestinal diseases and
gastrointestinal tumors under digestive endoscopy, especially endoscopic diagnosis of early cancer of the
digestive tract； 2. Endoscopic diagnosis and treatment of early gastrointestinal cancer, diagnosis and treatment of functional gastrointestinal diseases；3.Diagnosis and treatment of inflammatory bowel disease |
|
| Personal Profile | |
| He is mainly engaged in the diagnosis and treatment of gastrointestinal diseases and functional gastrointestinal diseases under digestive endoscopy, especially in the diagnosis and treatment of early gastrointestinal cancer. He completes more than 1000 cases of digestive endoscopy every year. He has published more than 100 papers as the first author and corresponding author, including more than 20 SCI papers. Presided over 7 projects at the national level, the provincial science and technology department, the provincial education commission, and the provincial health department, participated in the compilation of the books "Diagnostic Atlas of Early Gastrointestinal Cancer Blue Laser Imaging Technology" and "Practical Gastroenterology";.He trained more than 30 postgraduates and 4 doctoral students. | |
| Selected Publications | |
|
1．Double-nylon
purse-string suture in closing postoperative wounds following endoscopic
resection of large gastric submucosal
tumors.World Journal of Gastroenterology 2024. 2．A New Risk Score to Predict Intensive Care Unit Admission for Patients with Acute Pancreatitis 48 Hours After Admission: Multicenter Study.Digestive Diseases and Sciences 2023. 3．miR-200a attenuated oxidative stress, inflammation, and apoptosis in dextran sulfate sodium-induced colitis through activation of Nrf2.Frontiers in Immunology 2023. 4. Research hotspots and trend analysis of abdominal pain in inflammatory bowel disease: a bibliometric and visualized analysis.Frontiers in Pharmacology 2023. 5. A New Risk Score to Predict Intensive Care Unit Admission for Patients with Acute Pancreatitis 48 Hours After Admission: Multicenter Study.DIGESTIVE DISEASES AND SCIENCES 2022. 6. Machine learning model identifies aggressive acute pancreatitis within 48 h of admission: a large retrospective study.BMC MEDICAL INFORMATICS AND DECISION MAKING 2022. 7. CircRNA_0040705 promotes the progression of hepatocellular carcinoma. IUBMB LIFE 2022. 8. Inhibition of IRAK 1/4 alleviates colitis by inhibiting TLR4/ NF-κB pathway and protecting the intestinal barrier.Bosn J Basic Med Sci 2022. 9. Clinical Efficacy of Endoscopic Submucosal Dissection for the Treatment of Duodenal Lesions in Terms of Operative Technique and Management of Complications.J Laparoendosc Adv Surg Tech A 2022. 10. Real-time artificial intelligence for detecting focal lesions and diagnosing neoplasms of the stomach by white-light endoscopy(with videos).2021 11.Pristimerin reduces dextran sulfate sodium-induced colitis in mice by inhibiting microRNA-155.Int Immunopharmacol.2021 12.Real-time artificial intelligence for detecting focal lesions and diagnosing neoplasms of the stomach by white-light endoscopy(with videos).Gastrointest Endosc.2021 13.Application of linked color imaging in the diagnosis of early gastrointestinal neoplasms and precancerous lesions: a review.Therap Adv Gastroenterol.2021 14. Eriodictyol attenuates dextran sodium sulphate-induced colitis in mice by regulating the sonic hedgehog signalling pathway.Pharm Biol.2021 15. Reciprocal induction of hepatitis C virus replication and stimulation of hepatic profibrogenic cytokine release and cellular viability by YKL-40.Ann Transl Med.2021 16.Poly(ADP ribose) polymerase 1 inhibitor ameliorates dextran sulfate sodium induced.Exp Ther Med.2021 17.Clinical Efficacy of Single-Channel Gastroscopy, Double-Channel Gastroscopy, and Double Gastroscopy for Submucosal Tumors in the Cardia and Gastric Fundus.2020 18.Salidroside attenuates dextran sulfate sodium-induced colitis in mice via SIRT1/FoxOs signaling pathway.2019 19.Diagnostic value of blue laser imaging combined with magnifying endoscopy for precancerous and early gastric cancer lesions.2019 20.Diagnostic ability of blue laser imaging combined with magnifying endoscopy for early esophageal cancer.2019 |
学术任职与荣誉
科研成果
| 出诊医生 | 星期一 | 星期二 | 星期三 | 星期四 | 星期五 | 星期六 | 星期日 | |||||||
| 上午 | 下午 | 上午 | 下午 | 上午 | 下午 | 上午 | 下午 | 上午 | 下午 | 上午 | 下午 | 上午 | 下午 | |
| 沈磊 | ||||||||||||||
预约方式
武汉大学人民医院
湖北省人民医院