科室及职务
诊疗专长
| 姓名 | 周江桥 |
| 出生年月 | 1965年6月 |
| 单位 | 武汉大学人民医院 器官移植科 |
| 所属学科 | 临床医学-外科学 |
| 职务、职称及头衔 | 外科主任兼器官移植科主任，教授，一级主任医师，博士生导师 |
| zhoujq@whu.edu.cn | |
| 联系方式 | 027-88041911转81849或13907178286 |
| 研究方向 | 1.肾脏、肝脏缺血再灌注损伤；2.肾脏移植；3.移植免疫耐受 |
| 个人简介 | 从事器官移植工作三十余年，在器官移植领域，尤其是肾移植领域有丰富的临床经验和较高的学术造诣，在肾移植领域有丰富的临床经验和较高的学术造诣，开展亲属活体肾移植、跨血型肾移植、高致敏受体的肾移植、小儿供肾肾移植、儿童肾移植、肝肾联合移植、心肾联合移植以及各种肾移植术后并发症的治疗。曾多次赴欧美国家进行学术交流。至今已成功挽救了逾2500名尿毒症患者的生命，肾移植成功率在95%以上，达国内一流水平。工作以来，累计发表论文140余篇，其中SCI论文60余篇，主编专著《临床DCD肾移植实践》，参编专著8部，主持国家自然科学基金面上项目2项，主持或参与省市科研项目共计10余项，在研课题5项，曾获湖北省科技进步二等奖1项。 |
| 学术任职与荣誉 |
中华医学会器官移植学分会副主任委员 中国医师协会器官移植医师分会副会长 中华医学会器官移植分会肾移植学组副组长 国家卫健委COTRS科学委员会委员 中国医促会肾脏移植分会副主任委员 中国研究型医院学会器官移植专业委员会副主任委员 国家卫健委肾脏移植质控中心专家委员会委员 中国康复医学会器官移植康复专业委员会副主任委员 湖北省医学会器官移植分会副主任委员 《中华器官移植杂志》副总编辑 《中华移植杂志（电子版）》编委 《AJT》（中文版）编委 |
| 教育履历 |
2002-09至2005-06，武汉大学， 外科学， 博士 1990-09至1993-06，湖北医科大学，外科学， 硕士 1981-09至1986-06，湖北医科大学，临床医学， 学士 |
| 工作履历 |
2015-06至今， 武汉大学人民医院，器官移植科，一级主任医师，
教授 2005-01至2015-06，武汉大学人民医院，泌尿外科， 主任医师， 副教授 1998-01至2005-01，武汉大学人民医院，泌尿外科， 副主任医师 1993-01至1998-01，武汉大学人民医院，泌尿外科， 主治医师 |
| 成果获奖 | 曾获湖北省科技进步二等奖 |
| 代表性论著 |
[1]
Chen Z, Hu F, Zhang Y, Zhang L, Wang T, Kong C, Hu H, Guo J, Chen Q, Yu B,
Liu Y, Zou J, Zhou J, Qiu T. Ubiquitin-specific protease 29 attenuates
hepatic ischemia-reperfusion injury by mediating TGF-β-activated kinase 1
deubiquitination. Front Immunol. 2023 May 26;14:1167667. doi:
10.3389/fimmu.2023.1167667. PMID: 37304282. [2] Guo J, Han S, Chen Q, Wang T, Yu B, Zhou J, Qiu T. Analysis of potential immune-related genes involved in the pathogenesis of ischemia-reperfusion injury following liver transplantation. Front Immunol. 2023 Mar 16;14:1126497. doi: 10.3389/fimmu.2023.1126497. PMID: 37006305. [3] Liu Y, Qiu T, Chen Z, Ma X, Wang T, Zhang Y, Kong C, Yu B, Guo J, Zhou J. A case report of two Chinese monozygotic twins with NPHP1 gene-associated nephronophthisis undergoing kidney transplantation from a related living-donor. Transpl Immunol. 2023 Jun;78:101828. doi: 10.1016/j.trim.2023.101828. Epub 2023 Mar 21. PMID: 36948406. [4] Chen Q, Guo J, Qiu T, Zhou J. Mechanism of ASK1 involvement in liver diseases and related potential therapeutic targets: A critical pathway molecule worth investigating. J Gastroenterol Hepatol. 2023 Mar;38(3):378-385. doi: 10.1111/jgh.16087. Epub 2022 Dec 29. PMID: 36533997. [5] Zhou L, Han S, Guo J, Qiu T, Zhou J, Shen L. Ferroptosis-A New Dawn in the Treatment of Organ Ischemia-Reperfusion Injury. Cells. 2022 Nov 17;11(22):3653. doi: 10.3390/cells11223653. PMID: 36429080. [6] Guo J, Yu B, Zou J, Zhang L, Wang T, Zhou J, Qiu T. Correlation between CYP3A5 gene polymorphism and BK virus infection in kidney transplant recipients. Transpl Immunol. 2022 Dec;75:101709. doi: 10.1016/j.trim.2022.101709. Epub 2022 Sep 12. PMID: 36100194. [7] Guo J, Chen Z, Kong C, Yu B, Wang T, Zhang Y, Liu Y, Zhou J, Qiu T. Meta-analysis of echinocandins combined with trimethoprim-sulfamethoxazole for treatment of Pneumocystis pneumonia. J Chemother. 2023 May;35(3):181-187. doi: 10.1080/1120009X.2022.2095155. Epub 2022 Jul 9. PMID: 35815561. [8] Zhou J, Guo L, Ma T, Qiu T, Wang S, Tian S, Zhang L, Hu F, Li W, Liu Z, Hu Y, Wang T, Kong C, Yang J, Zhou J, Li H. N-acetylgalactosaminyltransferase-4 protects against hepatic ischemia/reperfusion injury by blocking apoptosis signal-regulating kinase 1 N-terminal dimerization. Hepatology. 2022 Jun;75(6):1446-1460. doi: 10.1002/hep.32202. Epub 2021 Dec 19. PMID: 34662438. [9] Qiu T, Wang T, Zhou J, Chen Z, Zou J, Zhang L, et al. DUSP12 protects against hepatic ischemia-reperfusion injury dependent on ASK1-JNK/p38 pathway in vitro and in vivo. Clin Sci (Lond) 2020; 134 (17): 2279-2294. doi: 10.1042/CS20191272. [10] Jiangqiao Z, Tianyu W, Zhongbao C, Long Z, Jilin Z, Xiaoxiong M, et al.Ubiquitin-Specific Peptidase 10 Protects Against Hepatic Ischaemic/Reperfusion Injury via TAK1 Signalling. Front Immunol 2020; 11 506275.doi: 10.3389/fimmu.2020.506275. [11] Zhou J, Wang T, Qiu T, Chen Z, Ma X, Zhang L, Zou J. Ubiquitin-specific protease-44 inhibits the proliferation and migration of cells via inhibition of JNK pathway in clear cell renal cell carcinoma.BMC Cancer. 2020 Mar 12;20(1):214. [12] Qiu Tao, Wang Tianyu, Zhou Jiangqiao, Chen Zhongbao, Ma Xiaoxiong, Zhang Long, Zou Jilin.Tripartite Motif 8 Deficiency Relieves Hepatic Ischaemia/reperfusion Injury via TAK1-dependent Signalling Pathways. Int J Biol Sci 2019;15(8):1618-1629.doi:10.7150/ijbs.33323 [13] Qiu T, Zhou J, Wang T, Chen Z, Ma X, Zhang L, Zou J.Leukocyte immunoglobulin-like receptor B4 deficiency exacerbates acute lung injury via NF-κB signaling in bone marrow-derived macrophages.Biosci Rep. 2019 Jun 14;39(6). pii: BSR20181888. [14] Jiangqiao Zhou,Tao Qiu,Tianyu Wang,Zhongbao Chen,Xiaoxiong Ma,Long Zhang,Jilin Zou,USP4 deficiency exacerbates hepatic ischaemia/reperfusion injury via TAK1 signalling,Clin Sci (Lond),2019,133(2):335-349. [15] Jiangqiao Z, Tao Q, Zhongbao C, Xiaoxiong M, Long Z, Jilin Z, Tianyu W, Anti-silencing function 1B histone chaperone promotes cell proliferation and migration via activation of the AKT pathway in clear cell renal cell carcinoma,Biochem Biophys Res Commun,2019,511(1):165-172. [16] Wang T, Qiu T, Yuan Y, Chen Z, Ma X, Zhang L, Jin Z, Zou J, Zhang Y, Zhou J. Summary report of seven cases of COVID-19 infection in renal transplant recipients. Transpl Immunol. 2021 Dec;69:101445. doi: 10.1016/j.trim.2021.101445. Epub 2021 Aug 10. PMID: 34384886; PMCID: PMC8352666. [17] Wang T, Qiu T, Wang M, Yuan Y, Chen Z, Ma X, Zhang L, Zou J, Jin Z, Xu Y, Zhang Y, Zhou J. A patient with end-stage renal disease who recovered from coronavirus disease 2019 then received a kidney transplant. Transpl Immunol. 2021 Aug;67:101395. doi: 10.1016/j.trim.2021.101395. Epub 2021 Apr 22. PMID: 33895261; PMCID: PMC8061181 [18] Zou J, Wang T, Qiu T, Chen Z, Zhou J, Ma X, Jin Z, Xu Y, Zhang L. Clinical characteristics of tuberculous infection following renal transplantation. Transpl Immunol. 2022 Feb;70:101523. doi: 10.1016/j.trim.2021.101523. Epub 2021 Dec 29. PMID: 34973371. [19] Zou J, Qiu T, Zhou J, Wang T, Ma X, Jin Z, Xu Y, Zhang L, Chen Z. Clinical Manifestations and Outcomes of Renal Transplantation Patients With Pneumocystis jirovecii Pneumonia and Cytomegalovirus Co-infection. Front Med (Lausanne). 2022 Apr 11;9:860644. doi: 10.3389/fmed.2022.860644. PMID: 35479953; PMCID: PMC9035925. [20] Zou J, Wang T, Qiu T, Chen Z, Zhou J, Ma X, Jin Z, Xu Y, Zhang L. Clinical characteristics of tuberculous infection following renal transplantation. Transpl Immunol. 2022 Feb;70:101523. doi: 10.1016/j.trim.2021.101523. Epub 2021 Dec 29. PMID: 34973371. |
| Name | JIANGQIAO ZHOU |
| Date of birth | June，1965 |
| Department | Department of Organ Transplantation，Renmin Hospital, Wuhan University |
| Title |
Chairman of Surgery
Department and Department of Organ Transplantation, Medical Doctor,
Professor, Director, Doctoral tutor |
| zhoujq@whu.edu.cn | |
| TEL | 027-88041911-81848 or 13907178286 |
| Research Direction | 1. Kidney and liver ischemia-reperfusion injury 2.Kidney transplantation 3. Transplant Immune tolerance |
| Personal Profile | Director Zhou has been engaged in organ transplantation for more than 30 years. He has rich clinical experience and high academic attainment in the field of organ transplantation, especially in the field of kidney transplantation. He has rich clinical experience and high academic attainment in the field of kidney transplantation. Kidney transplantation of living relatives, cross-blood type kidney transplantation, kidney transplantation of highly sensitized recipients, pediatric donor kidney transplantation, children's kidney transplantation, combined liver-kidney transplantation, combined heart-kidney transplantation and the treatment of complications after kidney transplantation. He has been to European and American countries for academic exchanges many times. So far, it has successfully saved the lives of more than 2,500 uremia patients, and the success rate of kidney transplantation is over 95%, reaching the first-class level in China. Since working, he has published more than 140 papers, including more than 60 SCI papers, edited the monograph "Clinical DCD Kidney Transplantation Practice", participated in the compilation of 8 monographs, presided over 2 general projects of the National Natural Science Foundation of China, presided over or participated in provincial and municipal scientific research There are a total of more than 10 projects, 5 research topics, and 1 second prize of Hubei Provincial Science and Technology Progress Award. |
| Selected Publications |
[1]
Chen Z, Hu F, Zhang Y, Zhang L, Wang T, Kong C, Hu H, Guo J, Chen Q, Yu B,
Liu Y, Zou J, Zhou J, Qiu T. Ubiquitin-specific protease 29 attenuates
hepatic ischemia-reperfusion injury by mediating TGF-β-activated kinase 1
deubiquitination. Front Immunol. 2023 May 26;14:1167667. doi:
10.3389/fimmu.2023.1167667. PMID: 37304282. [2] Guo J, Han S, Chen Q, Wang T, Yu B, Zhou J, Qiu T. Analysis of potential immune-related genes involved in the pathogenesis of ischemia-reperfusion injury following liver transplantation. Front Immunol. 2023 Mar 16;14:1126497. doi: 10.3389/fimmu.2023.1126497. PMID: 37006305. [3] Liu Y, Qiu T, Chen Z, Ma X, Wang T, Zhang Y, Kong C, Yu B, Guo J, Zhou J. A case report of two Chinese monozygotic twins with NPHP1 gene-associated nephronophthisis undergoing kidney transplantation from a related living-donor. Transpl Immunol. 2023 Jun;78:101828. doi: 10.1016/j.trim.2023.101828. Epub 2023 Mar 21. PMID: 36948406. [4] Chen Q, Guo J, Qiu T, Zhou J. Mechanism of ASK1 involvement in liver diseases and related potential therapeutic targets: A critical pathway molecule worth investigating. J Gastroenterol Hepatol. 2023 Mar;38(3):378-385. doi: 10.1111/jgh.16087. Epub 2022 Dec 29. PMID: 36533997. [5] Zhou L, Han S, Guo J, Qiu T, Zhou J, Shen L. Ferroptosis-A New Dawn in the Treatment of Organ Ischemia-Reperfusion Injury. Cells. 2022 Nov 17;11(22):3653. doi: 10.3390/cells11223653. PMID: 36429080. [6] Guo J, Yu B, Zou J, Zhang L, Wang T, Zhou J, Qiu T. Correlation between CYP3A5 gene polymorphism and BK virus infection in kidney transplant recipients. Transpl Immunol. 2022 Dec;75:101709. doi: 10.1016/j.trim.2022.101709. Epub 2022 Sep 12. PMID: 36100194. [7] Guo J, Chen Z, Kong C, Yu B, Wang T, Zhang Y, Liu Y, Zhou J, Qiu T. Meta-analysis of echinocandins combined with trimethoprim-sulfamethoxazole for treatment of Pneumocystis pneumonia. J Chemother. 2023 May;35(3):181-187. doi: 10.1080/1120009X.2022.2095155. Epub 2022 Jul 9. PMID: 35815561. [8] Zhou J, Guo L, Ma T, Qiu T, Wang S, Tian S, Zhang L, Hu F, Li W, Liu Z, Hu Y, Wang T, Kong C, Yang J, Zhou J, Li H. N-acetylgalactosaminyltransferase-4 protects against hepatic ischemia/reperfusion injury by blocking apoptosis signal-regulating kinase 1 N-terminal dimerization. Hepatology. 2022 Jun;75(6):1446-1460. doi: 10.1002/hep.32202. Epub 2021 Dec 19. PMID: 34662438. [9] Qiu T, Wang T, Zhou J, Chen Z, Zou J, Zhang L, et al. DUSP12 protects against hepatic ischemia-reperfusion injury dependent on ASK1-JNK/p38 pathway in vitro and in vivo. Clin Sci (Lond) 2020; 134 (17): 2279-2294. doi: 10.1042/CS20191272. [10] Jiangqiao Z, Tianyu W, Zhongbao C, Long Z, Jilin Z, Xiaoxiong M, et al.Ubiquitin-Specific Peptidase 10 Protects Against Hepatic Ischaemic/Reperfusion Injury via TAK1 Signalling. Front Immunol 2020; 11 506275.doi: 10.3389/fimmu.2020.506275. [11] Zhou J, Wang T, Qiu T, Chen Z, Ma X, Zhang L, Zou J. Ubiquitin-specific protease-44 inhibits the proliferation and migration of cells via inhibition of JNK pathway in clear cell renal cell carcinoma.BMC Cancer. 2020 Mar 12;20(1):214. [12] Qiu Tao, Wang Tianyu, Zhou Jiangqiao, Chen Zhongbao, Ma Xiaoxiong, Zhang Long, Zou Jilin.Tripartite Motif 8 Deficiency Relieves Hepatic Ischaemia/reperfusion Injury via TAK1-dependent Signalling Pathways. Int J Biol Sci 2019;15(8):1618-1629.doi:10.7150/ijbs.33323 [13] Qiu T, Zhou J, Wang T, Chen Z, Ma X, Zhang L, Zou J.Leukocyte immunoglobulin-like receptor B4 deficiency exacerbates acute lung injury via NF-κB signaling in bone marrow-derived macrophages.Biosci Rep. 2019 Jun 14;39(6). pii: BSR20181888. [14] Jiangqiao Zhou,Tao Qiu,Tianyu Wang,Zhongbao Chen,Xiaoxiong Ma,Long Zhang,Jilin Zou,USP4 deficiency exacerbates hepatic ischaemia/reperfusion injury via TAK1 signalling,Clin Sci (Lond),2019,133(2):335-349. [15] Jiangqiao Z, Tao Q, Zhongbao C, Xiaoxiong M, Long Z, Jilin Z, Tianyu W, Anti-silencing function 1B histone chaperone promotes cell proliferation and migration via activation of the AKT pathway in clear cell renal cell carcinoma,Biochem Biophys Res Commun,2019,511(1):165-172. [16] Wang T, Qiu T, Yuan Y, Chen Z, Ma X, Zhang L, Jin Z, Zou J, Zhang Y, Zhou J. Summary report of seven cases of COVID-19 infection in renal transplant recipients. Transpl Immunol. 2021 Dec;69:101445. doi: 10.1016/j.trim.2021.101445. Epub 2021 Aug 10. PMID: 34384886; PMCID: PMC8352666. [17] Wang T, Qiu T, Wang M, Yuan Y, Chen Z, Ma X, Zhang L, Zou J, Jin Z, Xu Y, Zhang Y, Zhou J. A patient with end-stage renal disease who recovered from coronavirus disease 2019 then received a kidney transplant. Transpl Immunol. 2021 Aug;67:101395. doi: 10.1016/j.trim.2021.101395. Epub 2021 Apr 22. PMID: 33895261; PMCID: PMC8061181 [18] Zou J, Wang T, Qiu T, Chen Z, Zhou J, Ma X, Jin Z, Xu Y, Zhang L. Clinical characteristics of tuberculous infection following renal transplantation. Transpl Immunol. 2022 Feb;70:101523. doi: 10.1016/j.trim.2021.101523. Epub 2021 Dec 29. PMID: 34973371. [19] Zou J, Qiu T, Zhou J, Wang T, Ma X, Jin Z, Xu Y, Zhang L, Chen Z. Clinical Manifestations and Outcomes of Renal Transplantation Patients With Pneumocystis jirovecii Pneumonia and Cytomegalovirus Co-infection. Front Med (Lausanne). 2022 Apr 11;9:860644. doi: 10.3389/fmed.2022.860644. PMID: 35479953; PMCID: PMC9035925. [20] Zou J, Wang T, Qiu T, Chen Z, Zhou J, Ma X, Jin Z, Xu Y, Zhang L. Clinical characteristics of tuberculous infection following renal transplantation. Transpl Immunol. 2022 Feb;70:101523. doi: 10.1016/j.trim.2021.101523. Epub 2021 Dec 29. PMID: 34973371. |
学术任职与荣誉
科研成果
| 出诊医生 | 星期一 | 星期二 | 星期三 | 星期四 | 星期五 | 星期六 | 星期日 | |||||||
| 上午 | 下午 | 上午 | 下午 | 上午 | 下午 | 上午 | 下午 | 上午 | 下午 | 上午 | 下午 | 上午 | 下午 | |
| 周江桥 | ||||||||||||||
预约方式
武汉大学人民医院
湖北省人民医院