科室及职务
诊疗专长
| 姓名 | 王博 |
| 出生年月 | 1987年9月 |
| 单位 | 武汉大学人民医院胸外科 |
| 所属学科 | 临床医学-外科学 |
| 职务、职称及头衔 | 科研秘书，临床药物试验基地秘书，副教授，副主任医师，硕士研究生导师 |
| rmh_wb@whu.edu.cn | |
| 联系方式 | 15971428123 |
| 研究方向 | 脓毒症肺损伤，缺血再灌注肺损伤的发病机制研究及临床防治 |
| 个人简介 | |
| 主要从事胸外科疾病的诊疗与科研工作，以项目负责人身份主持国自然科学基金，国家重点研发项目子任务，湖北省科技厅基金，武汉大学青年教师自主科研项目，武汉大学人民医院引导基金，武汉大学人民医院交叉项目（重点支助）等；以第一作者及通讯作者发表SCI论文10余篇，单篇最高影响因子为12.17分，核心期刊3篇。目前已培养科室多名硕士，博士研究生。 | |
| 学术任职与荣誉 | |
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中国抗癌协会康复分会胸科学组肺结节专委会委员_x005f 湖北省临床肿瘤学会肺癌青年委员会委员_x000b_湖北省临床肿瘤学会纵隔肿瘤专家委员会委员 湖北省临床肿瘤学会健康教育专委会秘书长 中国老年学和老年医学学会肿瘤康复分会委员 |
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| 教育履历 | |
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2006.09-2011.06广东医科大学基础医学院获得医学学士学位 2011.09-2016.06华中科技大学同济医学院第一临床学院硕博连读获得外科学博士学位 |
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| 工作履历 | |
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2016.07-2019.11武汉大学人民医院胸外科主治医师 2019.11-至今武汉大学人民医院胸外科副主任医师，副教授，硕士研究生导师 |
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| 成果获奖 | |
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1. 2023年武汉大学人民医院医疗菁英；2022年武汉大学人民医院医疗春苗；2021年度武汉大学人民医院医德医风先进个人；2020年度武汉大学人民医院五四青年奖章；2020年度武汉大学人民医院工会积极分子；2018年度武汉大学人民医院先进工作者；2020年度武昌方舱医院“抗疫先锋”； 2.2020年《肺移植缺血再灌注损伤机制及临床关键技术创新》获湖北省科技进步奖一等奖； 3.2017年《结肠代食管手术技术创新和临床推广应用》获湖北省科技进步推广奖二等奖； |
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| 代表性论著 | |
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1.Ning, L., Shishi, Z., Bo, W., & Huiqing, L.
(2023). Targeting immunometabolism against acute lung injury. Clinical
immunology (Orlando, Fla.), 249, 109289.
https://doi.org/10.1016/j.clim.2023.109289 2.Li, N., Liu, B., Xiong, R., Li, G., Wang, B., & Geng, Q. (2023). HDAC3 deficiency protects against acute lung injury by maintaining epithelial barrier integrity through preserving mitochondrial quality control. Redox biology, 63, 102746. https://doi.org/10.1016/j.redox.2023.102746 3.Xiong, R., Li, N., Xiong, J., Liu, B., He, R., Wang, B., & Geng, Q. (2023). Oral Hydroxychloroquine Mitigates Lipopolysaccharide-induced Lung Injury by Inhibiting Pyroptosis in Mice. Current molecular pharmacology, 16(3), 362–373. https://doi.org/10.2174/1874467215666220822110855 4.Li, N., Xiong, R., Li, G., Wang, B., & Geng, Q. (2023). PM2.5 contributed to pulmonary epithelial senescence and ferroptosis by regulating USP3-SIRT3-P53 axis. Free radical biology & medicine, 205, 291–304. https://doi.org/10.1016/j.freeradbiomed.2023.06.017 5.Li, N., Xiong, R., He, R., Liu, B., Wang, B., & Geng, Q. (2021). Mangiferin Mitigates Lipopolysaccharide-Induced Lung Injury by Inhibiting NLRP3 Inflammasome Activation. Journal of inflammation research, 14, 2289–2300. https://doi.org/10.2147/JIR.S304492 6.Xiong, R., Jiang, W., Li, N., Liu, B., He, R., Wang, B., & Geng, Q. (2021). PM2.5-induced lung injury is attenuated in macrophage-specific NLRP3 deficient mice. Ecotoxicology and environmental safety, 221, 112433. https://doi.org/10.1016/j.ecoenv.2021.112433 7.Li, G., Wang, B., Ding, X., Zhang, X., Tang, J., & Lin, H. (2021). Plasma extracellular vesicle delivery of miR-210-3p by targeting ATG7 to promote sepsis-induced acute lung injury by regulating autophagy and activating inflammation. Experimental & molecular medicine, 53(7), 1180–1191. https://doi.org/10.1038/s12276-021-00651-6 8.Wang, B., Cai, Z., Liu, B., Liu, Z., Zhou, X., Dong, N., & Li, F. (2017). RAGE deficiency alleviates aortic valve calcification in ApoE-/- mice via the inhibition of endoplasmic reticulum stress. Biochimica et biophysica acta. Molecular basis of disease, 1863(3), 781–792. https://doi.org/10.1016/j.bbadis.2016.12.012 9.Mao, Z., Wang, B., Dong, P., Liu, G., Hu, H., Zhang, S., Pan, S., & Huang, J. (2021). Reconstruction of the esophagus of patients with middle thoracic esophageal carcinoma using the remnant stomach following Billroth II gastrectomy. Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 34(1), doaa077. https://doi.org/10.1093/dote/doaa077 10.Wang, B., Zhang, X., Jiang, W., Huang, J., Chen, J., Kreisel, D., Danguilan, J. L. J., Hsin, M., & Lin, H. (2020). Double lung transplantation for end-stage Kartagener syndrome: a case report and literature review. Journal of thoracic disease, 12(4), 1588–1594. https://doi.org/10.21037/jtd.2020.02.28 11.Wang, B., Huang, J., Hsin, M., Chen, J., & Lin, H. (2021). First lung transplant in Wuhan for a critical and elderly COVID-19 patient. Immunity, inflammation and disease, 9(4), 1500–1507. https://doi.org/10.1002/iid3.501 12.Wang, B., Lin, H. Q., Li, F., Mao, Z. F., & Dong, N. G. (2020). Aβ40 Promotes the Osteoblastic Differentiation of Aortic Valve Interstitial Cells through the RAGE Pathway. Current medical science, 40(5), 931–936. https://doi.org/10.1007/s11596-020-2264-3 13.Ning, L., Rui, X., Bo, W., & Qing, G. (2021). The critical roles of histone deacetylase 3 in the pathogenesis of solid organ injury. Cell death & disease, 12(8), 734. https://doi.org/10.1038/s41419-021-04019-6 |
| Name | Wang Bo |
| Date of birth | September,1987 |
| Department | Department of thoracic surgery，Renmin Hospital of Wuhan University. |
| Title | Associate chief physician, associate Professor, master tutor |
| rmh_wb@whu.edu.cn | |
| TEL | 15971428123 |
| Research Direction | |
| Study on pathogenesis and clinical prevention of lung injury caused by sepsis and ischemia reperfusion | |
| Personal Profile | |
| He was mainly engaged in the diagnosis, treatment and scientific research of thoracic diseases. As the project leader, he presided over the National Natural Science Foundation of China, the fund of the Science and Technology Department of Hubei Province, the independent scientific research project of young teachers of Wuhan University, the Guiding Fund of the Renmin Hospital of Wuhan University, and the cross-project of the Renmin Hospital of Wuhan University. He published more than 10 SCI papers as the first author and corresponding author, with the highest impact factor score of 12.17 for a single paper. At present, he has trained a number of master's and doctoral students in the department. | |
| Selected Publications | |
|
1.Ning, L., Shishi, Z., Bo, W., & Huiqing,
L. (2023). Targeting immunometabolism against acute lung injury. Clinical
immunology (Orlando, Fla.), 249, 109289.
https://doi.org/10.1016/j.clim.2023.109289 2.Li, N., Liu, B., Xiong, R., Li, G., Wang, B., & Geng, Q. (2023). HDAC3 deficiency protects against acute lung injury by maintaining epithelial barrier integrity through preserving mitochondrial quality control. Redox biology, 63, 102746. https://doi.org/10.1016/j.redox.2023.102746 3.Xiong, R., Li, N., Xiong, J., Liu, B., He, R., Wang, B., & Geng, Q. (2023). Oral Hydroxychloroquine Mitigates Lipopolysaccharide-induced Lung Injury by Inhibiting Pyroptosis in Mice. Current molecular pharmacology, 16(3), 362–373. https://doi.org/10.2174/1874467215666220822110855 4.Li, N., Xiong, R., Li, G., Wang, B., & Geng, Q. (2023). PM2.5 contributed to pulmonary epithelial senescence and ferroptosis by regulating USP3-SIRT3-P53 axis. Free radical biology & medicine, 205, 291–304. https://doi.org/10.1016/j.freeradbiomed.2023.06.017 5.Li, N., Xiong, R., He, R., Liu, B., Wang, B., & Geng, Q. (2021). Mangiferin Mitigates Lipopolysaccharide-Induced Lung Injury by Inhibiting NLRP3 Inflammasome Activation. Journal of inflammation research, 14, 2289–2300. https://doi.org/10.2147/JIR.S304492 6.Xiong, R., Jiang, W., Li, N., Liu, B., He, R., Wang, B., & Geng, Q. (2021). PM2.5-induced lung injury is attenuated in macrophage-specific NLRP3 deficient mice. Ecotoxicology and environmental safety, 221, 112433. https://doi.org/10.1016/j.ecoenv.2021.112433 7.Li, G., Wang, B., Ding, X., Zhang, X., Tang, J., & Lin, H. (2021). Plasma extracellular vesicle delivery of miR-210-3p by targeting ATG7 to promote sepsis-induced acute lung injury by regulating autophagy and activating inflammation. Experimental & molecular medicine, 53(7), 1180–1191. https://doi.org/10.1038/s12276-021-00651-6 8.Wang, B., Cai, Z., Liu, B., Liu, Z., Zhou, X., Dong, N., & Li, F. (2017). RAGE deficiency alleviates aortic valve calcification in ApoE-/- mice via the inhibition of endoplasmic reticulum stress. Biochimica et biophysica acta. Molecular basis of disease, 1863(3), 781–792. https://doi.org/10.1016/j.bbadis.2016.12.012 9.Mao, Z., Wang, B., Dong, P., Liu, G., Hu, H., Zhang, S., Pan, S., & Huang, J. (2021). Reconstruction of the esophagus of patients with middle thoracic esophageal carcinoma using the remnant stomach following Billroth II gastrectomy. Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 34(1), doaa077. https://doi.org/10.1093/dote/doaa077 10.Wang, B., Zhang, X., Jiang, W., Huang, J., Chen, J., Kreisel, D., Danguilan, J. L. J., Hsin, M., & Lin, H. (2020). Double lung transplantation for end-stage Kartagener syndrome: a case report and literature review. Journal of thoracic disease, 12(4), 1588–1594. https://doi.org/10.21037/jtd.2020.02.28 11.Wang, B., Huang, J., Hsin, M., Chen, J., & Lin, H. (2021). First lung transplant in Wuhan for a critical and elderly COVID-19 patient. Immunity, inflammation and disease, 9(4), 1500–1507. https://doi.org/10.1002/iid3.501 12.Wang, B., Lin, H. Q., Li, F., Mao, Z. F., & Dong, N. G. (2020). Aβ40 Promotes the Osteoblastic Differentiation of Aortic Valve Interstitial Cells through the RAGE Pathway. Current medical science, 40(5), 931–936. https://doi.org/10.1007/s11596-020-2264-3 13.Ning, L., Rui, X., Bo, W., & Qing, G. (2021). The critical roles of histone deacetylase 3 in the pathogenesis of solid organ injury. Cell death & disease, 12(8), 734. https://doi.org/10.1038/s41419-021-04019-6 |
学术任职与荣誉
科研成果
| 出诊医生 | 星期一 | 星期二 | 星期三 | 星期四 | 星期五 | 星期六 | 星期日 | |||||||
| 上午 | 下午 | 上午 | 下午 | 上午 | 下午 | 上午 | 下午 | 上午 | 下午 | 上午 | 下午 | 上午 | 下午 | |
| 王博 | ||||||||||||||
预约方式
武汉大学人民医院
湖北省人民医院